2016年

You're showing us your "ability to do" in this application. Please describe also how you properly apply your powers to "things needed to be done." Explain why you want to join our Rochester community of independent thinkers who create positive change and make the world "ever better."

翻译：在这份申请里你正向我们展示你“有能力开始从事事业”。请也谈谈你会如何恰当的利用能力来完成“那些需要被完成的事业”。解释你为何想加入我校这一由独立思想家所组成的社区。社区成员们力图带来正面的变化并让世界“更加美好”（此即学校校训Meliora）。

解析：AADPS分类I-a+AADPS分类I-c

字数限制：250词

Cancer is caused by genetic malfunction induced unregulated cell growth. Traditional treatments, from surgery to chemotherapy, could hardly distinguish cancer cells from healthy ones, thus causing significant damage to the patient's body as well. Although the newest development of medical science employed antibodies that specifically target cancer cells, the antibody drugs are expensive and the procedure could take a longer time to work. This is a meaningful problem that I decided to tackle.

Having been pondering for some time, I recalled that a chemical named X shared some characteristics of antibodies. By binding X to the antibody with Y bonds, I can increase the rate of A cell attaching to the target cell, enhancing the engulfment. In this way, the antibody effect can be strengthened.

Using an antibody named Z which can cause the death of pancreatic acinar cells and decrease blood glucose level, I then designed an experiment to verify the effectiveness of my enhanced antibody on mice. The result showed that the level of B (a digestive enzyme indirectly produced by pancreatic acinar cells) decreased, which verified that X did not interfere with the essential functions of the antibody. Meanwhile, the blood glucose level decreased by 45% more with some dose-related effects. With the same concentration of the drug, a much better outcome was achieved. With this technology, patients will save 1/3 of their money and recover faster and better. That’s certainly a good start!

留学文书译文（机翻）：

癌症是由基因缺陷引起的不受调控的细胞生长引起的。传统的治疗方法，从手术到化疗，很难区分癌细胞和健康细胞，从而对患者的身体造成严重损害。尽管医学的最新发展采用了专门针对癌细胞的抗体，但抗体药物价格昂贵，而且这一过程可能需要更长的时间。这是我决定解决的一个有意义的问题。

经过一段时间的思考，我回忆起一种名为X的化学物质具有抗体的某些特征。通过用Y键将X与抗体结合，我可以提高细胞附着到靶细胞的速率，增强吞噬。这样可以增强抗体的作用。

使用一种名为Z的抗体可以导致胰腺腺泡细胞死亡并降低血糖水平，然后我设计了一个实验来验证我的增强抗体对小鼠的有效性。结果表明，B（胰腺腺泡细胞间接产生的一种消化酶）水平下降，这证明X不干扰抗体的基本功能。同时，血糖水平下降了45%以上，并有一定的剂量相关效应。在相同浓度的药物下，取得了更好的结果。有了这项技术，患者将节省三分之一的钱，恢复得更快更好。这当然是一个好的开始！

标化条件：GPA 3.7 TOEFL 105 ACT 32

AADPS老师文书点评：如果有科研或项目经历，罗彻斯特大学的留学文书题目是一个绝好的平台，可以让你充分展示自己的灵感和创新。

家长感言：AADPS顾问的理工科背景让孩子的留学文书如虎添翼，成为了美本申请过程中至关重要的一环。